The virus that causes Covid-19 is developing resistance to two drugs used to treat patients with infections, scientists now say. In the first study, 156 Covid-19 patients were treated with the antiviral drug and observed over a span of two years between 2021-2023. Immune systemA higher likelihood of having viruses with changes that are resistant to nirmatrelvir was found in patients who took the antiviral treatment. Patients who took nirmatrelvir and those who had a compromised immune system had more pronounced effects. When the researchers arranged its DNA pattern, the Covid-19 virus infecting the patients was found to have developed a lower sensitivity level to both nirmatrelvir and remdesivir drugs.