With humanitarian funding slashed by the US and other countries, this year’s global health headlines have made grim reading. First new type of malaria treatment in decadesAfter successful clinical trials, the first new type of malaria treatment in decades is to seek regulatory approval. GanLum, from pharma company Novartis, outperformed the standard treatment by demonstrating a cure rate of 99.2% compared with 96.7% from the standard treatment. Crucially, it should also be effective against malaria parasites that have developed resistance to artemisinin — a component of the current standard treatment. In the 1990s, resistance to chloroquine, then the standard malaria treatment, led to millions of deaths, says Dr George Jagoe of the Medicines for Malaria Venture.

But the initial case for HS2 had been given as increasing capacity on the 700-mile West Coast Main Line which runs between London Euston and Glasgow. Andrew Meaney, partner at economics and finance consultancy Oxera, was asked by the Transport Select Committee in 2011 to analyse the business case for HS2. Speaking about the 'benefit-cost ratio', which compares the economic benefits to its costs, he told the podcast: 'The way these benefits are calculated, a lot of it comes from bypass schemes. He said: 'We were expecting a Rolls Royce business case at that point. This included an updated assessment of the value of business travellers' time, given all the technological advancements over the decade.

This Boxing Day was a sad blot on English top-flight history thanks to the Premier League and Sky - but my day at Stockport County reminded me of all that's beautiful about this treasured tradition, writes OLIVER HOLT

Drug dealers could not quite believe the message sent to them by the administrators of the Encrochat network in June 2020. Unfortunately the drug dealers were about to realise the advice offered to them was academic and binning the device pointless. The Liverpool man was found guilty after a protracted trial and jailed for 25 years. The Liverpool man disappeared after being released from custody and is now thought to be overseas. I think the most interesting point is howEncrochat has unearthed a whole swathe of low key drug dealers who were anonymous.

The traditional Peard Cup final took place on St Stephen’s Day at Garryduff, with C of I B facing Bandon. The tempo lifted in the second quarter, and the first real opportunity of the match fell to James Taylor, whose shot drifted wide of the target. A C of I B short corner was initially cleared, but during the second phase a shot was blocked on its way to goal, resulting in a penalty stroke. Bandon pressed hard in the final quarter and were rewarded with five minutes remaining when Ali Smith converted a penalty stroke following a last-ditch, mistimed challenge. However, C of I B held their nerve in the closing moments to secure a deserved 2–1 victory to claim the Peard Cup.

Well personal trainer Nancy Seal says getting abs in your fifties is achievable if you make a few simple tweaks to your daily routine - including engaging your core every time you walk through a door. 'Everybody has abs they're just sometimes hidden beneath a layer of fat, and it's easier to shred than you would think.' 'As long as your abs are pulled in and pelvic muscles are pulled up, you're giving them a workout and encouraging definition. 'It's important to visualise the plate of food that's shown to children in primary school. 'So take it easy, enjoy the workouts you do and always remember - abs in shoulders back!'

The Global Times compared the film to 'Schindler's List' and called 'Evil Unbound' a 'history lesson Japan must not miss'. Following the unexpected postponement of 'Evil Unbound' from July to September, China Central Television reposted the trailer on Weibo with the message: 'The truth cannot be forgotten.' He had written a textbook about the Nanjing Massacre and Unit 731 but the Ministry of Education demanded that passages dealing with those atrocities be deleted or revised. Pictured: Digging at Unit 731Chinese archaeologists in 2023 excavated a research facility hidden five feet underground, they that believed was the largest and most frequently used test site for Unit 731. Despite being sworn to secrecy, former members of Unit 731 have been driven by guilt to speak out about the crimes they were complicit in during the war.

Daily Mail analysis today lays bare the impact of the Government's decision to ditch the two-child benefit cap. Reeves' decision to lift the cap will benefit 470,000 bigger families on benefits, costing the taxpayer £3.2billion a year. The Conservatives have already pledged to restore the two-child cap if they win power. In her response to Ms Reeves' plan to scrap the two-child benefit cap while raising taxes on working people, Conservatives leader Kemi Badenoch branded the announcement a 'Benefits Street Budget'. A government spokesman said: 'This is an extreme hypothetical example that doesn't reflect how the benefit system works in practice for the vast majority of families on Universal Credit.

The widespread frost is expected in the final nights of 2025. Photo: Damien StoranThe final days of 2025 will stay “cool, cloudy and dry”, Met Éireann has said, but the nights are expected to bring temperatures below freezing and widespread frost. However, it will remain less cold near eastern coasts, with temperatures between 4 and 7C. Sunday night will be dry and cloudy, with the chance of isolated drizzle patches in the east and south. “And it will be cold by night with temperatures widely falling below freezing and widespread frost developing.

But thanks to Princess Anne's youngest granddaughter, seven-year-old Lena Tindall, hand-me-downs have been given the royal stamp of approval. She stepped out for the Christmas Day service at Sandringham wearing a coat that has had not one but two previous royal owners. Lena's cousin, Savannah, first wore the coat for Christmas in 2017, when she was the same age. Lena's older sister Mia, then eight, wore it to attend Prince Philip's memorial service in March 2022. Lady Louise's coat was a Prada design her mother wore for Ascot's Christmas racing weekend in 2015.

Dermot Bannon on haters, housing and his health: ‘I was weeks away from a heart attack – I was terrified’The Room to Improve hosts talks about his spats with homeowners, how prioritising his health in 2025 helped him lose 7 kilos and why he’s turned down Dancing with the Stars numerous times but would love to be on The TraitorsDermot Bannon reveals how he keeps things fresh after all the yearsTanya Sweeney Today at 06:30Here’s one thing I certainly didn’t expect Dermot Bannon to say: that when it comes to the way he lives his life and the way he treats people, Cilla Black has proved to be a major influence.

Their chase was set up by Australia’s second batting collapse of the match: 132 all out, to go with their opening-day 152. There were four wickets for Brydon Carse and three for Ben Stokes, who helped make up for a hamstring injury to Gus Atkinson, of which more below. After all, before this series, there had been only two two-day finishes in Australia, in 1930-31 and 2022-23. Now Gus Atkinson leaves the field on the second day in Melbourne, which will probably mean a first Ashes Test for Matthew Potts at Sydney. After carving Ben Stokes to Harry Brook at second slip for 19, he incurred the commentary-box wrath of former Australia opener Simon Katich, who fumed: ‘It’s pre-determined rubbish.

Heaven earned man of the match honours for his display at Old Trafford after helping the Red Devils secure a clean sheet in their victory against the Magpies. Speaking to Sky Sports as the man of the match winner, Heaven outlined the club's lofty aspirations. ‌View 2 Images Ayden Heaven has shared the high hopes he has for Man United (Image: Ash Donelon, Manchester United via Getty Images)Heaven has previously voiced his confidence that United will return to UEFA competitions next season. Ruben Amorim also weighed in on when United might next clinch the league title, ahead of their final match before Christmas against Aston Villa. Join our new MAN UTD WhatsApp community and receive your daily dose of Manchester United content from Mirror Football.

More than 70 XL Bully dogs destroyed since ban on breed came into effectStrict measures were introduced after a number of attacks on peopleOwnership of an XL bully without a certificate of exemption is now banned. Stock imageConor Feehan Today at 06:30Seventy-three XL Bully dogs have been put down around the country since a ban on the breed came into effect last February, figures released by the Department of Agriculture have revealed.

One of those books, The Dublin Pub: A Social and Cultural History, comes from the pen of Donal Fallon, a social historian whose writing sings. The Irish Pub: Invention and Re-invention, from Cork University Press, does something similar. It is also interesting to see an exploration of how the Irish pub was invented and how it became a global symbol of Irishness. Does this matter?” The only pity is that the cover price of €59, not at all unusual for an academic book, means The Irish Pub might not reach as wide an audience as it deserves to. Alcohol's ugly sideOn a separate, rather sober note: Irish pub culture is joyous, colourful and celebrated, but so many have fallen foul of the very thing that oils its wheels; alcohol.