The 48-week trial involved patients with severe asthma who required oral corticosteroids on top of the standard regimen, the drugmakers said in a joint statement, adding that the drug was compared against placebo. Tezepelumab works by blocking a type of immune protein called thymic stromal lymphopoietin (TSLP). TSLP belongs to the cytokine group, that is responsible for sending messages and sounding an alarm to the body’s immune system, and can also trigger inflammation. Data from the clinical study will be analysed further, the companies said, and details will be presented at a forthcoming medical conference. Tezepelumab had met the primary goal of another trial by significantly reducing asthma attacks for people with severe forms of the condition compared to a placebo, data in November showed.

Source: bd News24 December 22, 2020 08:03 UTC