“There is a theoretical risk that if you get a third dose of Astra, your body already has pre-formed antibodies against that third dose. A human body fully inoculated with Astrazeneca already has pre-formed antibodies to prevent severe COVID-19 infections. This may also hold true, again theoretical, with the other adenovirus vaccines like Jassen and Gamaleya,” Salvana said. (In fact, the Gamaleya Center actually used different adenovirus for the first and the second dose precisely because they were really afraid of the preformed antibodies against the adenovirus. This means that health workers can get a booster in November if they got their second dose of the COVID-19 vaccine on or before May, or in August for one-dose vaccines.

Source: Philippine Daily Inquirer November 17, 2021 22:38 UTC