“Pretty soon, the disease’s intensity will be low and it will become difficult” to gauge efficacy in a vaccine trial. In the United States, the Trump administration has pledged to pursue a vaccine at “warp speed,” plugging the possibility of having something ready by the end of the year. “I hope — I don’t want to see a lot of infections in the United States. ADDavid Heymann, an infectious-disease specialist at the London School of Hygiene and Tropical Medicine, noted that vaccine trials are especially hard when people are in lockdown. Another option for researchers would be “human challenge trials,” where healthy volunteers are given a vaccine and intentionally “challenged” with the coronavirus.

Source: Washington Post June 10, 2020 11:00 UTC