DoxyVAC: This study from 2022 in France looked at the effects of DoxyPEP (as well as the meningococcal B vaccine) in men who have sex with men. Researchers found that DoxyPEP managed to prevent about half of gonorrhoea cases, an improvement from what the IPERGAY study found five years earlier. These trials have indicated that DoxyPEP is 70-89 per cent effective at preventing chlamydia and 73-87 per cent effective at preventing a syphilis infection. In the UK, there are quite high levels of resistance to doxycycline, making it less clear how effective DoxyPEP could be if rolled out in the country. “But some of the evidence in terms of how effective DoxyPEP is at preventing gonorrhoea is a bit more mixed.

Source: The Times January 25, 2024 10:26 UTC