Experts call for broader alcohol intolerance testingBy Jonathan Chin / Staff writer, with CNAMedical experts yesterday called for broader testing for alcohol intolerance in Taiwan given the high prevalence of the disorder and its impact on health. Photo: APAlcohol intolerance is caused by mutations of the genes governing the enzymes that break down alcohol, Nien said. Alcohol is metabolized by alcohol dehydrogenase into acetaldehyde before acetaldehyde dehydrogenase (ALDH) breaks down the substance into carbon dioxide and water, which are expelled, she said. For people with alcohol intolerance, the low-activity ALDH enzymes cause toxic acetaldehyde to build up in the body, resulting in heightened risks of poisoning and cancer, Nien said. Susceptibility to hangovers, nausea, vertigo and developing a flush after drinking are common symptoms of alcohol intolerance, but genetic testing is required for a diagnosis, she said.

Source: Taipei Times December 23, 2025 17:14 UTC