Study explains why adults’ hearts don't regenerateAs heart cells mature in mice, the number of communication pathways called nuclear pores dramatically decreases, according to new research. While this might protect the organ from damaging signals, it could also prevent adult heart cells from regenerating, the researchers found. The study, published today in Developmental Cell, suggests that quieting communication between heart cells and their environment protects this organ from harmful signals related to stresses such as high blood pressure, but at the cost of preventing heart cells from receiving signals that promote regeneration. While skin and many other tissues of the human body retain the ability to repair themselves after injury, the same isn't true of the heart. During human embryonic and fetal development, heart cells undergo cell division to form the heart muscle.

Source: dna November 08, 2022 18:08 UTC