So what are the top five deadliest major cities in the U.S.? Baton Rouge, LouisianaBaton Rouge, Louisiana's state capital, is the nation's fifth deadliest city. New Orleans, LouisianaLouisiana is the only state to have two cities in the top five deadliest U.S. cities list. Though Baltimore's murder rate remained high, its overall crime rate dropped by nearly 60% between the mid 1990s and the mid 2010s. St. Louis, MissouriSt. Louis earned the title of deadliest city in America with a murder rate of 60.9 per 100,000 in 2018.

Source: Fox News January 28, 2020 21:00 UTC