The new protein, dubbed HexaPro, is also more stable than the team’s earlier version of the S protein, which according to the scientists should make it easier to store and transport. They said the new S protein also keeps its shape under heat stress, during storage at room temperature, and through multiple freeze-thaws -- qualities that are desirable in a robust vaccine. They then created 100 different versions of the protein by inserting the genetic blueprints for each version into a different culture of human cells. The scientists said their earlier S protein version forms the basis of vaccine candidates currently in human clinical trials, including the mRNA-1273 developed by the American biotechnology company Moderna. They said such vaccine candidates use modified versions of the viral genetic material to create coronavirus proteins in human cells for triggering an immune response.

Source: Hindustan Times July 24, 2020 08:48 UTC