healthUpdated: Aug 28, 2020 14:07 ISTIn an effort to understand why men are at greater risk for more severe symptoms and worse outcomes from COVID-19 regardless of age, scientists at Wake Forest School of Medicine conducted a review of published preclinical data on sex-specific hormone activity, especially estrogen. The review has been published in the September online issue of the journal Current Hypertension Reports. The review, they said, also pointed to estrogen’s lowering the level of ACE2 in the heart, which may modulate the severity of COVID-19 in women. Conversely, higher levels of ACE2 in tissues could account for why symptoms are worse in men than women, Groban said. (This story has been published from a wire agency feed without modifications to the text.

Source: Hindustan Times August 28, 2020 08:26 UTC